Pierre Nel, 17 July 2024 As requested, some feedback for you. These animals were treated immediately after loading from nets - no adult rams. So adult females & young rams received 8 mg perphenazine hydrochloride (water-based perphenazine /WBP), the smaller ones we titrated down. With haloperidol, there’s often still quite a few jumping and milling around. An hour or so later. I was very happy with the state of tranquillisation. Not too dopey or flat but very calm. Ulf Tubessing, [17 Jul 2024 at 18:22:39]: Thanks Pierre. This is what we find here as well (with slightly higher dosages). Interestingly enough, I darted an impala (actually many, but one was interesting) with 10 mg water-based perphenazine (WBP) in the dart. It was down within 3 minutes, loaded and transported over 300 km, all perfectly OK and calm at loading from boma. At point of offloading to another boma, one was dead. They put the rest of the group in a kraal and left the dead one in the passage for disposal in the morning. When they arrived in the morning, the dead one was happily walking up and down passage in boma. Similar story with a lechwe. Lesson: WBP can knock the odd animal out completely, but they tend to just sleep it off and get up a few hours later. Pierre Nel, 18 July 2024 Thanks Ulf. Good to know. It seems WBP is a few up on haloperidol. Did the Akineton make a difference to the flat one? Ulf Tubessing, 18 July 2024. Yes, according to the game dealer, it was responsive within 5 minutes and standing normally by 10 min. I find individual variation with regard to susceptibility to WBP. If I for instance move 18-month-old sable bulls out of breeding camps, I routinely add 20 mg WBP to the dart, but to get a more consistent dart make-up, I will draw up the combinations I need and mix darts for 5 animals in a 5 ml syringe, mix the contents well and then load 5 darts. There is thus no chance of difference in drugs in dart and even so, 1/30 animals may show excessive sedation after reversal. Akineton sorts them out within 10 min. At this stage, it is part of my reversal regime in animals not responding as they should.
