Alex Lewis, [20 Oct 2022 at 18:04:31]: Any suggestions for 2-day or more long tranquiliser for 4-5 month old lions. Any suggestions on dart combination to work with tranquillisers? Henry Labuschagne, [20 Oct 2022 at 18:12:36]: I use medetomidine 1mg per 50kg and ketamine 100mg for every 1mg medetomidine. Reverse with atipamezole 2.5mg per 1mg medetomidine. Spray Pet Remedy on front legs and in crate. Alex Lewis, [20 Oct 2022 at 18:16:27]: Thanks. What about Acuphase? Henry Labuschagne, [20 Oct 2022 at 18:22:53]: There are claims of liver issues in lions after Acuphase, so I avoid. Chat to Andy Fraser. He uses different combos and gets good results. Alex Lewis, [20 Oct 2022 at 19:20:33]: What about ketamine plus valium? Top up with valium? Peter Rogers, [20 Oct 2022 at 21:07:01]: There is nothing wrong with Acuphase. I have used it many times over many many years - don’t fix what ain’t broken . WBP not necessarily the answer here.