Annie Mears: Can anyone advise on best long acting antibiotics for crocodiles? Henry Labuschagne, [01 Sep 2022 at 09:40:20]: What do you want to treat ? Have you done culture and antibiogram? New research show crocodile blood has potent antibacterial properties. I have used Oxytet LA. I would assume Draxxin would be fine to use if indicated. Roy Bengis, [01 Sep 2022 at 17:36:01]: Just remember that reptiles, being poikilothermic, metabolise drugs much slower than mammals or birds.